The Reactive Trigger would increase your firing rate, which with co2 would at very least cause dropoff in velocity shot to shot. A very common side effect that is VERY annoying with co2 in rapid fire is icing. A lot of us have seen some nasty cases of people getting fingers stuck to guns that way and skin being lost, which I'm gathering you don't want happening to you. Also, I think the piston mechanism of the reactive trigger might have problems with co2 in terms of freezing the seals, which would be annoying to have to fix. You could use co2, but you'd have to be very careful, with remote probably being the safest way to go.