If you are thinking of putting Co2 on a Matrix you can.And they run well but it will wear your bolt o-rings down very fast and they aint cheap and also Co2 freezes your gun so runing it on air would be your best bet
The matrix will run fine on co2 but as said will freeze real fast so you need good gloves.
As for the o rings as long as you greese it up well they are fine.